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Flights from Portland to Santiago
Cheap flight deals from Portland to Santiago
We've found these cheap flights for you. You can book one-way or round-trip flight tickets.
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Round-trip
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One way
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PWM 07:1223h 33m1 stopsSCL 06:45Portland - Santiago | Sun, Jun 8 | Jetblue AirwaysSCL 22:5514h 28m1 stopsPWM 13:23Santiago - Portland | Sun, Jun 15 | LATAM AirlinesHK$7,322 HK$24,28570% OFF70% OFFHK$24,285 HK$7,322
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PWM 06:3024h 15m1 stopsSCL 06:45Portland - Santiago | Thu, Jun 19 | Delta Air LinesSCL 20:4015h 10m1 stopsPWM 11:50Santiago - Portland | Sun, Jun 22 | Delta Air LinesHK$10,150 HK$24,28557% OFF57% OFFHK$24,285 HK$10,150
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PWM 12:5518h 5m1 stopsSCL 07:00Portland - Santiago | Thu, Jun 19 | LATAM AirlinesSCL 20:4015h 10m1 stopsPWM 11:50Santiago - Portland | Sun, Jun 22 | LATAM AirlinesHK$11,263 HK$24,28554% OFF54% OFFHK$24,285 HK$11,263
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PWM 14:2016h 25m1 stopsSCL 06:45Portland - Santiago | Thu, Jun 19 | Jetblue AirwaysSCL 22:5514h 59m1 stopsPWM 13:54Santiago - Portland | Sun, Jun 22 | LATAM AirlinesHK$12,14750% OFFHK$24,285 HK$12,147
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PWM 14:3422h 31m1 stopsSCL 13:05Portland - Santiago | Sun, Jun 8 | Delta Air LinesSCL 07:0517h 41m1 stopsPWM 00:46Santiago - Portland | Sun, Jun 15 | LATAM AirlinesHK$21,85710% OFFHK$24,285 HK$21,857
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PWM 13:0017h 25m1 stopsSCL Invalid DatePortland - Santiago | Tue, May 20 | Normal AirlineSCL 15:006hNonstopPWM 16:00Santiago - Portland | Thu, May 22 | Normal AirlineFind More FlightsFind More Flights
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PWM 06:3524h 10m1 stopsSCL 06:45Portland - Santiago | Thu, May 22 | Delta Air LinesHK$4,226 HK$7,29342% OFF42% OFFHK$7,293 HK$4,226
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PWM 07:0223h 43m1 stopsSCL 06:45Portland - Santiago | Tue, Jun 10 | American AirlinesHK$4,240 HK$7,29342% OFF42% OFFHK$7,293 HK$4,240
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PWM 15:3515h 10m1 stopsSCL 06:45Portland - Santiago | Wed, May 21 | Jetblue AirwaysHK$4,276 HK$7,29341% OFF41% OFFHK$7,293 HK$4,276
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PWM 15:3515h 10m1 stopsSCL 06:45Portland - Santiago | Thu, May 22 | Jetblue AirwaysHK$4,27641% OFFHK$7,293 HK$4,276
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PWM 15:3515h 10m1 stopsSCL 06:45Portland - Santiago | Mon, May 19 | Jetblue AirwaysHK$4,42939% OFFHK$7,293 HK$4,429
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PWM 06:1024h 35m1 stopsSCL 06:45Portland - Santiago | Thu, May 22 | United AirlinesHK$4,49638% OFFHK$7,293 HK$4,496
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PWM 11:0719h 38m1 stopsSCL 06:45Portland - Santiago | Thu, May 22 | American AirlinesHK$4,83334% OFFHK$7,293 HK$4,833
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PWM 06:3524h 10m1 stopsSCL 06:45Portland - Santiago | Mon, May 19 | Delta Air LinesHK$5,24728% OFFHK$7,293 HK$5,247
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PWM 06:3524h 10m1 stopsSCL 06:45Portland - Santiago | Tue, May 20 | Delta Air LinesHK$5,25428% OFFHK$7,293 HK$5,254
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PWM 15:3521h 30m1 stopsSCL 13:05Portland - Santiago | Sun, Jun 8 | Jetblue AirwaysHK$6,56410% OFFHK$7,293 HK$6,564
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PWM 13:0017h 25m1 stopsSCL Invalid DatePortland - Santiago | Tue, May 20 | Normal AirlineFind More FlightsFind More Flights
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Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.
Flight Info | Portland to Santiago
Cheapest one-way flight price | HK$4,225 |
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Off-season for travel | April |
Peak season for travel | April |
Flight distance | 8,566.5 km |
Popular airline | American Airlines |
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Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Frequently Asked Questions
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When are flight tickets from Portland (PWM) to Santiago (SCL) the cheapest?
Airlines adjust prices for flights from Portland to Santiago based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays. -
How much do flights from Portland (PWM) to Santiago (SCL) cost?
According to Trip.com's data, the lowest price is around HK$10,421.
How to find a cheap flight from Portland to Santiago
Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Portland to Santiago. Book your flights at the right time and save more.
Be flexible with your travel dates to get the cheapest Portland to Santiago ticket.
Tap "Date" in the flight search bar to browse the calendar and find airfare from Portland to Santiago for the next six months in 2025. If you're looking to fly within the next three months, the lowest fare is HK$4226 for a one-way ticket on Thu, May 22.
Compare cheap Portland to Santiago flight deals from hundreds of airlines.
Our powerful search system compares prices from over 500 airlines. So you can find the cheapest flights from Portland to Santiago. The most affordable airline currently operating on this route is Delta Air Lines.
Set up a Price Alert to track fare drops.
Set up a Price Alert for your Portland to Santiago route to track ticket prices effortlessly—no need to check manually every day.
Don't miss out on cheap Portland to Santiago flight deals and promo codes.
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Book early or wait unitl the last minute to fine the best fares.
It's always better to book early! Airlines typically release their lowest fares about a year before departure, so check as soon as flights become available. If you miss that window, you may still find great deals closer to your travel date.
Search for flights on the go.
For the best booking experience on the go, download Trip.com and search for cheap flights from Portland to Santiago to access exclusive deals just for you.
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