Cheap flight deals from Myrtle Beach to Des Moines

We've found these cheap flights for you. You can book one-way or round-trip flight tickets.

Round-trip
One way

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

When is the cheapest time to fly from Myrtle Beach to Des Moines?

We monitor flight fares to help you find the best deals effortlessly

Cheapest flights

From price

May

27 4
4 11
11 18
18 25
Jun

25 1
1 8
8 15
15 22
22 29
Jul

29 6
6 13
13 20

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

When are flight tickets from Myrtle Beach (MYR) to Des Moines (DSM) the cheapest?

Airlines adjust prices for flights from Myrtle Beach to Des Moines based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
How much do flights from Myrtle Beach (MYR) to Des Moines (DSM) cost?

According to Trip.com's data, the lowest price is around Rp 7,685,517.

How to find a cheap flight from Myrtle Beach to Des Moines

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Myrtle Beach to Des Moines. Book your flights at the right time and save more.

Be flexible with your travel dates to get the cheapest Myrtle Beach to Des Moines ticket.

Tap "Date" in the flight search bar to browse the calendar and find airfare from Myrtle Beach to Des Moines for the next six months in 2025. If you're looking to fly within the next three months, the lowest fare is Rp 2236795 for a one-way ticket on Tue, Apr 29.

Compare cheap Myrtle Beach to Des Moines flight deals from hundreds of airlines.

Our powerful search system compares prices from over 500 airlines. So you can find the cheapest flights from Myrtle Beach to Des Moines. The most affordable airline currently operating on this route is Delta Air Lines.

Set up a Price Alert to track fare drops.

Set up a Price Alert for your Myrtle Beach to Des Moines route to track ticket prices effortlessly—no need to check manually every day.

Don't miss out on cheap Myrtle Beach to Des Moines flight deals and promo codes.

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Book early or wait unitl the last minute to fine the best fares.

It's always better to book early! Airlines typically release their lowest fares about a year before departure, so check as soon as flights become available. If you miss that window, you may still find great deals closer to your travel date.

Search for flights on the go.

For the best booking experience on the go, download Trip.com and search for cheap flights from Myrtle Beach to Des Moines to access exclusive deals just for you.

Flight Info | Myrtle Beach to Des Moines

Cheapest one-way flight price	Rp 2,236,795
Off-season for travel	March
Peak season for travel	March
Flight distance	1,556.44 km
Popular airline	Delta Air Lines