Cheap flight from Medellin to Santiago from Rp 2,636,403
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Flights from Medellin to Santiago
Cheap flight deals from Medellin to Santiago
We've found these cheap flights for you. You can book one-way or round-trip flight tickets.
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Round-trip
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One way
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Cheapest nonstop
MDE 17:555h 55mNonstopSCL 00:50Medellin - Santiago | Sun, Jun 8 | avianca
SCL 01:556h 15mNonstopMDE 07:10Santiago - Medellin | Thu, Jun 12 | aviancaRp 5,849,872 Rp 6,794,22214% OFF14% OFFRp 6,794,222 Rp 5,849,872 -
MDE 17:555h 55mNonstopSCL 00:50Medellin - Santiago | Sun, Jun 1 | avianca
SCL 01:556h 15mNonstopMDE 07:10Santiago - Medellin | Thu, Jun 5 | aviancaRp 5,910,973 Rp 6,794,22213% OFF13% OFFRp 6,794,222 Rp 5,910,973
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MDE 18:098h 52m1 stopsSCL 04:01Medellin - Santiago | Thu, May 15 | JetSMART
SCL 04:5113h 29m1 stopsMDE 17:20Santiago - Medellin | Fri, May 23 | JetSMARTRp 4,987,667 Rp 6,794,22227% OFF27% OFFRp 6,794,222 Rp 4,987,667 -
MDE 18:098h 52m1 stopsSCL 04:01Medellin - Santiago | Wed, May 7 | JetSMART
SCL 04:5113h 29m1 stopsMDE 17:20Santiago - Medellin | Wed, May 14 | JetSMARTRp 5,166,44424% OFFRp 6,794,222 Rp 5,166,444
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MDE 18:098h 52m1 stopsSCL 04:01Medellin - Santiago | Wed, Jun 4 | JetSMART
SCL 06:108h 44m1 stopsMDE 13:54Santiago - Medellin | Tue, Jun 10 | aviancaRp 5,309,01422% OFFRp 6,794,222 Rp 5,309,014
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MDE 18:098h 52m1 stopsSCL 04:01Medellin - Santiago | Fri, Jun 6 | JetSMART
SCL 06:108h 44m1 stopsMDE 13:54Santiago - Medellin | Mon, Jun 9 | aviancaRp 5,309,01422% OFFRp 6,794,222 Rp 5,309,014
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MDE 15:1412h 3m1 stopsSCL 04:17Medellin - Santiago | Fri, May 16 | JetSMART
SCL 04:5113h 29m1 stopsMDE 17:20Santiago - Medellin | Sun, May 18 | JetSMARTRp 5,523,99919% OFFRp 6,794,222 Rp 5,523,999
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MDE 18:098h 52m1 stopsSCL 04:01Medellin - Santiago | Sat, Jun 7 | JetSMART
SCL 04:5113h 29m1 stopsMDE 17:20Santiago - Medellin | Thu, Jun 12 | JetSMARTRp 5,535,31419% OFFRp 6,794,222 Rp 5,535,314
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MDE 13:228h 8m1 stopsSCL 22:30Medellin - Santiago | Thu, May 15 | avianca
SCL 04:5113h 29m1 stopsMDE 17:20Santiago - Medellin | Fri, May 23 | JetSMARTRp 5,625,83417% OFFRp 6,794,222 Rp 5,625,834
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MDE 17:1010h 7m1 stopsSCL 04:17Medellin - Santiago | Sun, May 18 | JetSMART
SCL 15:339h 4m1 stopsMDE 23:37Santiago - Medellin | Sun, May 25 | JetSMARTRp 5,689,19916% OFFRp 6,794,222 Rp 5,689,199
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MDE 14:0013h 17m1 stopsSCL 04:17Medellin - Santiago | Mon, Jun 2 | JetSMART
SCL 15:339h 39m1 stopsMDE 00:12Santiago - Medellin | Mon, Jun 9 | JetSMARTRp 5,732,19616% OFFRp 6,794,222 Rp 5,732,196
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MDE 05:5315h 37m1 stopsSCL 22:30Medellin - Santiago | Wed, Jun 4 | avianca
SCL 06:108h 44m1 stopsMDE 13:54Santiago - Medellin | Tue, Jun 10 | aviancaRp 5,759,35215% OFFRp 6,794,222 Rp 5,759,352
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MDE 13:0017h 25m1 stopsSCL Invalid DateMedellin - Santiago | Thu, May 8 | Normal Airline
SCL 15:006hNonstopMDE 16:00Santiago - Medellin | Sat, May 10 | Normal AirlineFind More FlightsFind More Flights
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Cheapest nonstop
MDE 17:555h 55mNonstopSCL 00:50Medellin - Santiago | Wed, Jun 4 | aviancaRp 3,659,282 Rp 5,394,80032% OFF32% OFFRp 5,394,800 Rp 3,659,282
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MDE 17:555h 55mNonstopSCL 00:50Medellin - Santiago | Fri, Jun 6 | aviancaRp 3,659,282 Rp 5,394,80032% OFF32% OFFRp 5,394,800 Rp 3,659,282
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MDE 18:098h 52m1 stopsSCL 04:01Medellin - Santiago | Wed, May 7 | JetSMART AirlinesRp 2,636,403 Rp 5,394,80051% OFF51% OFFRp 5,394,800 Rp 2,636,403
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MDE 18:098h 52m1 stopsSCL 04:01Medellin - Santiago | Mon, Jun 2 | JetSMART AirlinesRp 2,849,12547% OFFRp 5,394,800 Rp 2,849,125
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MDE 18:098h 52m1 stopsSCL 04:01Medellin - Santiago | Mon, Jun 9 | JetSMART AirlinesRp 2,858,17747% OFFRp 5,394,800 Rp 2,858,177
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MDE 18:298h 32m1 stopsSCL 04:01Medellin - Santiago | Tue, May 20 | JetSMART AirlinesRp 2,864,96647% OFFRp 5,394,800 Rp 2,864,966
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MDE 18:298h 32m1 stopsSCL 04:01Medellin - Santiago | Tue, May 6 | JetSMART AirlinesRp 2,898,91146% OFFRp 5,394,800 Rp 2,898,911
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MDE 18:098h 52m1 stopsSCL 04:01Medellin - Santiago | Thu, May 15 | JetSMART AirlinesRp 2,921,54246% OFFRp 5,394,800 Rp 2,921,542
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MDE 18:098h 52m1 stopsSCL 04:01Medellin - Santiago | Wed, Jun 4 | JetSMART AirlinesRp 2,926,06846% OFFRp 5,394,800 Rp 2,926,068
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MDE 18:098h 52m1 stopsSCL 04:01Medellin - Santiago | Thu, May 29 | JetSMART AirlinesRp 2,926,06846% OFFRp 5,394,800 Rp 2,926,068
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MDE 18:098h 52m1 stopsSCL 04:01Medellin - Santiago | Sat, May 10 | JetSMART AirlinesRp 4,446,80818% OFFRp 5,394,800 Rp 4,446,808
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MDE 15:1212h 5m1 stopsSCL 04:17Medellin - Santiago | Fri, May 9 | JetSMART AirlinesRp 4,693,47613% OFFRp 5,394,800 Rp 4,693,476
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MDE 13:0017h 25m1 stopsSCL Invalid DateMedellin - Santiago | Thu, May 8 | Normal AirlineFind More FlightsFind More Flights
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Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.
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Cheapest Airlines flying from Medellin to Santiago
Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.
Frequently Asked Questions
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When are flight tickets from Medellin (MDE) to Santiago (SCL) the cheapest?
Airlines adjust prices for flights from Medellin to Santiago based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays. -
How much do flights from Medellin (MDE) to Santiago (SCL) cost?
According to Trip.com's data, the lowest price is around Rp 5,953,970. -
How long does it take to fly from Medellin (MDE) to Santiago (SCL) and what is the distance?
It takes around 7 hours 8 minutes to fly from Medellin (MDE) to Santiago (SCL). -
What are the most popular airlines that fly from Medellin (MDE) to Santiago (SCL)?
Airlines with flights from Medellin (MDE) to Santiago (SCL): JetSMART Airlines.
How to find a cheap flight from Medellin to Santiago
Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Medellin to Santiago. Book your flights at the right time and save more.
Be flexible with your travel dates to get the cheapest Medellin to Santiago ticket.
Tap "Date" in the flight search bar to browse the calendar and find airfare from Medellin to Santiago for the next six months in 2025. If you're looking to fly within the next three months, the lowest fare is Rp 3659282 for a one-way ticket on Wed, Jun 4.
Compare cheap Medellin to Santiago flight deals from hundreds of airlines.
Our powerful search system compares prices from over 500 airlines. So you can find the cheapest flights from Medellin to Santiago. The most affordable airline currently operating on this route is avianca.
Set up a Price Alert to track fare drops.
Set up a Price Alert for your Medellin to Santiago route to track ticket prices effortlessly—no need to check manually every day.
Don't miss out on cheap Medellin to Santiago flight deals and promo codes.
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Book early or wait unitl the last minute to fine the best fares.
It's always better to book early! Airlines typically release their lowest fares about a year before departure, so check as soon as flights become available. If you miss that window, you may still find great deals closer to your travel date.
Search for flights on the go.
For the best booking experience on the go, download Trip.com and search for cheap flights from Medellin to Santiago to access exclusive deals just for you.
Flight Info | Medellin to Santiago
| Cheapest one-way flight price | Rp 2,636,402 |
|---|---|
| Cheapest round-trip ticket price | Rp 5,849,872 |
| Off-season for travel | February |
| Peak season for travel | June |
| Flight distance | 4,435.22 km |
| Average flight time | 7 hours 8 minutes |
| Popular airline | avianca |
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